Chubby♨️@kimmonismus · X剑桥大学研究人员开展了据称全球首个AI设计疫苗成分的人体试验。该疫苗使用AI设计的“超级抗原”，旨在训练免疫系统对抗包括现有新冠变种及可能引发未来大流行的动物冠状病毒在内的广泛冠状病毒家族。首次人体试验仅39人，主要验证安全性。免疫反应虽属中等，但被视为有前景，证明AI设计的疫苗抗原可以在人体中测试。下一步计划进行约200人的更大规模研究。
We are in for a wild ride， and this is just the beginning： 'World-first' vaccine designed by artificial intelligence
Researchers at the University of Cambridge have trialled what they describe as the world's first AI-designed vaccine component in humans.
The vaccine uses an AI-designed "super-antigen" intended to train the immune system against a broad family of coronaviruses， including existing Covid variants and animal coronaviruses that could potentially cause future pandemics.
Instead of designing a vaccine around one current virus strain， researchers fed AI genetic data from many known coronaviruses. The AI then designed an antigen meant to trigger immune protection across the whole virus family， even if the virus mutates or jumps from animals to humans.
The first human trial involved 39 people and mainly tested safety. The immune response was described as modest， but the result is still seen as promising because it shows that an AI-designed vaccine antigen can be tested in humans.
A larger study with around 200 people will now examine how well the vaccine actually trains the immune system.