Claude Fable 5 不会回答基础生物学问题
Anthropic 发布 Claude Fable 5，宣称其为迄今最强大的广泛可用模型，并称赞其生物学能力。但该模型设计上拒绝回答高中水平的基础生物学问题，而是将此类查询转交给上一代旗舰模型 Claude Opus 4.8。原因是 Fable 属于 Mythos 类模型，网络安全能力极强，Anthropic 认为将其完全公开过于危险，因此在公开版本中刻意限制部分能力。
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Claude Fable won’t answer basic biology questions
To protect against bioweapons, Anthropic told The Verge Fable’s ‘overly conservative’ safeguards block ‘most queries tied to biology work.’
To protect against bioweapons, Anthropic told The Verge Fable’s ‘overly conservative’ safeguards block ‘most queries tied to biology work.’
Anthropic just released Claude Fable 5, calling it the most powerful AI model it has ever made widely available and praising its skills in biology, among others. But the model won’t answer basic biology questions — the kind you’d expect a high schooler to handle. Instead, it hands off the query to the former flagship model, Claude Opus 4.8.
It isn’t because Fable doesn’t know the answers. It’s because Anthropic won’t let it, by design.
Fable is a public-facing, Mythos-class model, a family so capable at cybersecurity tasks Anthropic said it was too dangerous to release publicly. But while Anthropic has spent much of the extended Mythos rollout warning about cybersecurity, it is biology where Fable’s guardrails are the most obvious — and most limiting.
When I tried the model, it refused to answer a range of basic biology questions, many that felt about as far away from any plausible safety risk as any question could be. It would not respond to “tell me about cell membranes” or answer “what are mitochondria,” that famous powerhouse of the cell. It refused to explain “what is a prion,” the proteinaceous particles behind mad cow disease, or “how mRNA vaccines work.”
“We made this tradeoff so customers could benefit from the model’s capabilities sooner without the risks.”
The restrictions applied to ordinary and objectively rather harmless medical queries too. Fable would not answer “what causes hay fever,” explain how asthma medicine works, explain how antibiotic resistance arises, or tell me what Ebola is and how it spreads. Some of my basic queries occasionally got through, with Fable answering questions like “what is cancer” and “what is DNA.” When Fable refused, Opus 4.8 generally answered perfectly well.